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Haemoprotozoal infections

Malaria
Amoebiasis
Trypanosomiasis
Leishmaniasis
Toxoplasmosis

Malaria

3-3.5 million death/ each year
40 % population lives in malaria endemic area
Pakistan has one case/1000 population
Males and females - equally affected
All age groups are affected

Life cycle

Fatigue
Malaise
Shaking chills
Arthralgia
Myalgia
Cough
Nausea
Vomiting

Clinical features

Tachycardia
Hypotension
Anemia
Splenomegaly
Jaundice

Cutaneous manifestations

Mosquito bite skin reaction

Flushing of face

Profuse sweating

Jaundice

Bleeding gums

Conjunctival petechiae

Cutaneous petechiae

Cuatneous petechiae

Skin problems due to drugs

Pruritis

Steven johnson syndrome

Toxic epidermal necrolysis

Urtricaria

Erythema multiforme

Steven johnson syndrome

urticaria

Thick and thin blood film
Complete blood picture
Electrolytes
Renal function test
Micro hematocrit centrifugation
Polymerase chain reaction
Immunochromatographic test

Investigations

Prevention

Mosquito repellants

Proper clothings

Mosquito nets

Chloroquine sensitive species:

Chloroquine

Primaquine

Severe attacks

Quinine dihydrochloride

Artemether

Chloroquine resistant species:

Malarone Qunine plus one of the following

1. Doxycycline

2.Clindamycin

3.Tetracycline Artesunate

Haemolytic anemia
Cerebral malaria
Acute tubular necrosis
Hypotension
Shock
Acute respiratory distress syndrome

Acute hepatopathy
Cardiac arrythmias
Lactic acidosis
Electrolyte imbalance
DIC
Relapses ( ovale ,vivax)
Nephrotic syndrome ( P.malaraie)

TREATMENTS

Severe attacks:

Parenteral antimalarials

Artemether

Artesunate followed by

mefloquine

Qunine plus

I/V Tetracycline or Clindamycin

Complications

TODAY NEW

Case Presentation by

DrZahid And Dr Hassan

(12thJune,2009)

TODAY NEWS

Topic Presentation

Haemoprotozoal Infection

by,Dr SM Kashif and Dr Hassan

(14th June2009)

Picture Of the Week

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